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In a healthy digestive tract, different types of bacteria live in harmony and contribute to health, metabolism of nutrients, detoxification, pathogen resistance, immunity, neurotransmitter regulation, and inflammatory control. When dysbiosis occurs and gut microbes are imbalanced, you are vulnerable to a myriad of health issues and need to consume a probiotic supplement that will replenish beneficial bacteria and restore healthy balance to the intestines.
After a digestive insult caused by antibiotics or dietary toxins, your gut is often starved of the healthy bacteria that properly digest foods and eliminate waste. This can lead to diarrhea, bloating, and abdominal discomfort. Support Biotic contains seven of the most researched probiotic strains to help resolve GI distress and improve overall vitality.
Shelf-Stable Freeze-Dried Bacteria Strains
Prime Probiotic Support contains seven strains of Lactobacillus, Bifidobacterium, and Saccharomyces to properly balance your intestinal environment and encourage the growth of more beneficial bacteria. In addition to aiding digestion, these strains support a healthy enteric nervous system. which is essential to immunity. This unique system of 100s of millions of nerve cells line your GI tract and act as a 2nd brain, controlling things like enzyme production, and modulation of neurotransmitters. Improper neurotransmitter levels can seriously affect emotional regulation and are yet another reason to use high quality probiotics. *
The Prime Probiotic Support Advantage
Many of the strains sold in probiotic formulas are barely studied or have isolated benefits. Support Biotic was intentionally formulated with 7 strains known to work and work synergistically in a safe and effective manner. Our use of freeze-dried HOWARU® strains ensures that you receive an uncompromised dose of the highest quality probiotics with every capsule.
The Strains
- Lactobacillus acidophilus: To nourish your gut’s healthy bacteria and fight bloating, abdominal pain, and diarrhea by defending against dietary toxins and “bad” bacteria.
- Lactobacillus rhamnosus: A powerful strain that can survive the harsh conditions of the stomach and nourish your gut’s microbial lining.
- Lactobacillus paracasei: To help balance inflammatory molecules and target cholesterol and fat balance within your digestive tract.
- Lactobacillus plantarum: To support the growth of the healthy gut bacteria that can defend against abdominal symptoms and strengthen your gut-brain barrier.
- Bifidobacterium lactis: To support nutrient absorption and defend against harmful and potentially life-threatening strains of bacteria.
- Bifidobacterium bifidum: To enhance your gut immunity by targeting inflammation, immune cell function, and mucosal defenses.
- Saccharomyces boulardii: A potent yeast that promotes your gut barrier by resisting your stomach environment, targeting harmful bacteria, and supporting healthy stool formation.
The freeze-dried patented stabilization technology from HOWARU® labs allows our formula to survive the harsh gastrointestinal environment and adhere to the intestinal tract to deliver superior results. No refrigeration is required, even after opening. *
Science-Based Ingredients
- Lactobacillus acidophilus (La-14): This bacterial strain is naturally found within your intestines and works to enhance sugar digestion and cholesterol balance [1,2]. This strain supports mucosal defenses and gut function by releasing lactic acid and hydrogen peroxide, which neutralize damaging dietary toxins and supports the suppression of “bad” bacteria [3.4].
- Lactobacillus rhamnosus (Lr-32): Since this bacterial strain can withstand the extreme pH ranges within your body, it is uniquely positioned to thrive within your gut [5]. By nourishing your healthy gut flora, rhamnosus supports the strength of your gut barrier, which defends against diarrhea and abdominal symptoms [6]. This feature is especially important when taking antibiotics, as they strip the intestinal mucosa of their protective bacterial defenders. L. rhamnosus may also help to build defenses against certain gut-mediated allergies [7].
- Lactobacillus paracasei (Lpc-37): This immunity-supporting probiotic strain targets the intestinal bacteria and promotes the balance of inflammatory mediators and key cells, called T-helper cells [8]. Its properties may also support cholesterol balance and optimize fat storage [9,10].
- Lactobacillus plantarum (Lp-115): As a member of the Lactobacillus genus, this strain is well-suited for the harsh conditions of the gut. Multiple clinical trials have suggested that plantarum may support the number of beneficial gut bacteria, which can lead to less diarrhea, bloating, and other inflammation-related symptoms [11]. This bacterial strain may also support memory, a balanced mood, and overall cognitive performance [12].
- Bifidobacterium lactis (BI-04): This bacterial strain supports vitamin and mineral absorption, in addition to enhancing the immune response. It also supports the creation of an environment that may suppress the growth of life-threatening bacteria, such as Enterobacteriaceae and Clostridium [13]. Studies even suggest a strengthened immune response in vaccinated infants born to mothers who supplemented with lactis [14].
- Bifidobacterium bifidum (Bb-06): This strain plays a significant role in gut barrier strength, which is essential to a branch of the immune system called innate immunity [15]. This strain interferes with inflammatory pathways and supports the function of immune cells, called white blood cells. Additionally, in response to facilitating mucin breakdown, bifidum supports mucin production to strengthen mucosal defenses against pathogens [16].
- Saccharomyces boulardii (SNZ 1986):This beneficial yeast possesses several unique qualities, including an ability to survive at the low pH and harsh conditions of your stomach [17]. It also works to preferentially block the ability of harmful bacteria to thrive. In this way, boulardii supports your gut’s lining from damaging toxins and harmful bacteria that can cause diarrhea [18]. By targeting the intestinal wall, this strain may support stool caliber and quality [19].
FAQ: Prime Probiotic Support
Is this formula really shelf-stable and not requiring refrigeration?
Yes, patented freeze-dried strains are used to ensure stability.
The capsules are small compared to other brands. Why?
Many formulas add a lot of fillers to their capsules, and in the case of probiotics, these capsules are often 60-75% full of filler. We use as little filler material as possible.
Can I open the capsules and pour the powder into food or drinks?
This is not recommended, because you want the capsule to break up while in the stomach for optimal release into the intestines.
References
- Savaiano DA. Lactose digestion from yogurt: mechanism and relevance. Am J Clin Nutr. 2014;99(5 Suppl):1251S-5S. doi:10.3945/ajcn.113.073023
- Rerksuppaphol S, Rerksuppaphol L. A Randomized Double-blind Controlled Trial of Lactobacillus acidophilus Plus Bifidobacterium bifidum versus Placebo in Patients with Hypercholesterolemia. J Clin Diagn Res. 2015;9(3):KC01-KC4. doi:10.7860/JCDR/2015/11867.5728
- Ahrne S, Hagslatt ML. Effect of lactobacilli on paracellular permeability in the gut. Nutrients. 2011;3(1):104-117. doi:10.3390/nu3010104
- Sinn DH, Song JH, Kim HJ, et al. Therapeutic effect of Lactobacillus acidophilus-SDC 2012, 2013 in patients with irritable bowel syndrome. Dig Dis Sci. 2008;53(10):2714-2718. doi:10.1007/s10620-007-0196-4
- Corcoran BM, Stanton C, Fitzgerald GF, Ross RP. Survival of probiotic lactobacilli in acidic environments is enhanced in the presence of metabolizable sugars. Appl Environ Microbiol. 2005;71(6):3060-3067. doi:10.1128/AEM.71.6.3060-3067.2005
- Evans M, Salewski RP, Christman MC, Girard SA, Tompkins TA. Effectiveness of Lactobacillus helveticus and Lactobacillus rhamnosus for the management of antibiotic-associated diarrhoea in healthy adults: a randomised, double-blind, placebo-controlled trial. Br J Nutr. 2016;116(1):94-103. doi:10.1017/S0007114516001665
- Ozdemir O. Various effects of different probiotic strains in allergic disorders: an update from laboratory and clinical data. Clin Exp Immunol. 2010;160(3):295-304. doi:10.1111/j.1365-2249.2010.04109.x
- Ichikawa S, Miyake M, Fujii R, Konishi Y. Orally administered Lactobacillus paracasei KW3110 induces in vivo IL-12 production. Biosci Biotechnol Biochem. 2009;73(7):1561-1565. doi:10.1271/bbb.90058
- Domingos-Lopes MFP, Stanton C, Ross RP, Silva CCG. Histamine and cholesterol lowering abilities of lactic acid bacteria isolated from artisanal Pico cheese. J Appl Microbiol. 2020;129(6):1428-1440. doi:10.1111/jam.14733
- Aronsson L, Huang Y, Parini P, et al. Decreased fat storage by Lactobacillus paracasei is associated with increased levels of angiopoietin-like 4 protein (ANGPTL4). PLoS One. 2010;5(9):e13087. Published 2010 Sep 30. doi:10.1371/journal.pone.0013087
- Ducrotté P, Sawant P, Jayanthi V. Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome. World J Gastroenterol. 2012;18(30):4012-4018. doi:10.3748/wjg.v18.i30.4012
- Lew LC, Hor YY, Yusoff NAA, et al. Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study. Clin Nutr. 2019;38(5):2053-2064. doi:10.1016/j.clnu.2018.09.010
- Szajewska H, Guandalini S, Morelli L, Van Goudoever JB, Walker A. Effect of Bifidobacterium animalis subsp lactis supplementation in preterm infants: a systematic review of randomized controlled trials. J Pediatr Gastroenterol Nutr. 2010;51(2):203-209. doi:10.1097/MPG.0b013e3181dc0d93
- Prescott SL, Wickens K, Westcott L, et al. Supplementation with Lactobacillus rhamnosus or Bifidobacterium lactis probiotics in pregnancy increases cord blood interferon-gamma and breast milk transforming growth factor-beta and immunoglobin A detection [published correction appears in Clin Exp Allergy. 2009 May;39(5):771]. Clin Exp Allergy. 2008;38(10):1606-1614. doi:10.1111/j.1365-2222.2008.03061.x
- Turroni F, Taverniti V, Ruas-Madiedo P, et al. Bifidobacterium bifidum PRL2010 modulates the host innate immune response. Appl Environ Microbiol. 2014;80(2):730-740. doi:10.1128/AEM.03313-13
- Bunesova V, Lacroix C, Schwab C. Mucin Cross-Feeding of Infant Bifidobacteria and Eubacterium hallii. Microb Ecol. 2018;75(1):228-238. doi:10.1007/s00248-017-1037-4
- Pais P, Almeida V, Yılmaz M, Teixeira MC. Saccharomyces boulardii: What Makes It Tick as Successful Probiotic?. J Fungi (Basel). 2020;6(2):78. Published 2020 Jun 4. doi:10.3390/jof6020078
- Surawicz CM, Elmer GW, Speelman P, McFarland LV, Chinn J, van Belle G. Prevention of antibiotic-associated diarrhea by Saccharomyces boulardii: a prospective study. Gastroenterology. 1989;96(4):981-988. doi:10.1016/0016-5085(89)91613-2
- Bleichner G, Bléhaut H, Mentec H, Moyse D. Saccharomyces boulardii prevents diarrhea in critically ill tube-fed patients. A multicenter, randomized, double-blind placebo-controlled trial. Intensive Care Med. 1997;23(5):517-523. doi:10.1007/s001340050367
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.